• HIV-seropositive patients should not be refused ICU admission based merely on the patient’s HIV-serostatus
  • All HIV-seropositive patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) who are mechanically ventilated should be managed using the same protocols for management of ALI/ARDS as among general populations – with low tidal volumes and controlled plateau pressures, for example using the ARDS Network guidelines
  • Expert daily consultation between HIV and ICU physicians is essential in the management of critically-ill HIV-seropositive patients admitted to the ICU. In some cases this expertise will be obtained by transfer of the patient to a tertiary centre
  • HIV medication should be reviewed regularly for toxicity and drug interactions. In some circumstances it may be more appropriate to change HIV therapy rather than dose modify. Advice should be sought from an HIV clinician and/or pharmacist prior to planned modification of cART