Drug Characteristics
  • Formulation

    245 mg tablets 

    co formulated with emtricitabine as Truvada

    co formulated with efavirenz and emtricitabine as Atripla

    co formulated with emtricitabine and rilpivirine as Eviplera

    co formulated with cobicistat, elvitegravir, and emtricitabine as Stribild

  • Dose

    245mg daily

    Infant 13 mg/kg as a single dose within 12 hours of life.

  • Side Effects

    Potential to impair renal function

  • Interactions

    Avoid other nephrotoxic  medication

  • Renal

    Test renal function and serum phosphate before treatment, then every 4 weeks (more frequently if at increased risk of renal impairment) for 1 year and then every 3 months, interrupt treatment if renal function deteriorates or serum phosphate decreases.

  • Hepatic

    Active against hepatitis B, risk of flare if treatment interupted

  • Pregnancy

    FDA catagery B

    Tenofovir should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

  • Other Information