Drug Characteristics
  • Formulation

    150mg tablets

    300mg tablets

    • co formulated with Abacavir as KIVEXA
    • co formulated with Zidovudine and Abacavir as Trizivir
  • Dose

    300mg daily in 1 or 2 doses

    infant 2 mg/kg twice daily

  • Side Effects

    peripheral neuropathy

  • Interactions

    Do not use with Emtricitabine 

  • Renal

    reduce dose if eGFR less than 50 mL/minute/1.73 m2

  • Hepatic

    Active against hepatitis B. Risk of flare if treatment interupted

  • Pregnancy

    FDA catagory C 

    Lamivudine should be used during pregnancy only if the potential benefits outweigh the risks.

  • Other Information