Drug Characteristics
  • Formulation

    Tablet: 7.5 mg

    Unlicensed in UK, available from special order manufacturers

  • Dose

    PCP treatment

    30 mg orally once a day (in combination with clindamycin) for 21 days

  • Side Effects

    Methaemoglobinaemia, nausea, vomiting, haemolytic anaemia

    Not to be used in patients with G6PD deficient individuals

  • Interactions

    No specific drug interactions

  • Renal

    Dose in normal renal function

  • Hepatic

    Metabolized via the liver. No data on dose reduction in hepatic dysfunction

  • Pregnancy

    Limited Human Data – Probably Compatible

  • Other Information