Drug Characteristics
  • Formulation

    Tablets: 100mg, 400mg, 400mg in 5ml suspension available as a special

  • Dose

    Atypical mycobacterial infections (MAI): 15 mg/kg orally once a day (as part of a combination regimen)

  • Side Effects

    Visual disturbances (optic neuritis), gastrointestinal disturbances, rash

  • Interactions

    No significant drug interactions

  • Renal

    GFR 20–50: Dose as in normal renal function

    GFR 10–20: 15 mg/kg every 24–36 hours, or 7.5–15 mg/kg/day

    GFR <10: 15 mg/kg every 48 hours, or 5–7.5 mg/kg/day        

  • Hepatic

    No data on dose reduction in hepatic dysfunction

    It should be used with caution and under strict medical supervision in impaired liver function.        

  • Pregnancy

    Compatible

  • Other Information